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Digital twins
Updated on Apr 29, 2025

15 Digital Twin Applications/ Use Cases by Industry in 2025

15 digital twin applications and use cases by industry15 digital twin applications and use cases by industry

Digital twin technology is becoming more widespread. According to Deloitte study, the global market for digital twins is expected to grow with 38% CAGR to reach $16 billion by 2023, and the proliferation of IoT technology accelerating this growth. 1

Digital twin applications

Supply Chain

Digital twins are also widely used in the supply chain/logistics industry. Some applications include:

Predicting the performance of packaging materials

product packaging can be virtualized and then tested for errors before being packaged. Digital twins help logistics companies determine material feasibility.

Enhancing shipment protection

Logistics companies can analyze how different packaging conditions can affect product delivery with the help of digital twins.

Optimizing warehouse design and operational performance

Digital twins enable logistics companies to test warehouse layouts so companies can choose the most efficient warehouse design to maximize operational performance.

Creating a logistics network

A digital twin of a road network carries information about the traffic situation, road layout, and construction. With that knowledge, logistics companies can design the distribution routes and inventory storage locations.

Construction

A digital twin can help construction firms understand how a building is performing in real-time, which allows them to tweak performance to optimize efficiency. Data collected from digital twin can be used for planning and designing future buildings.

Healthcare

It’s been reported that 66% of healthcare executives expect increasing investment in digital twins over the next three years.2 Digital twins can help healthcare providers virtualize healthcare experience to optimize patient care, cost, and performance.

Top use cases of digital twin of healthcare include:

The visual summarizes the top 3 use cases of digital twin healthcare

Digital twin of a healthcare facility

Digital twin technology can be used to generate a virtual twin of a hospital to review operational strategies, capacities, staffing, and care models to identify areas of improvement, predict future challenges, and optimize organizational strategies. Therefore, digital twins of hospitals can be used for generating facility replicas, and in turn this enables:

  • Resource optimization: Leveraging historical and real-time data of hospital operations and surrounding environment (e.g. COVID-19 cases, car crashes, etc.) to create digital twins enables hospital management to detect bed shortages, optimize staff schedules, and help operate rooms. Such information increases the efficiency of resources and optimized the hospital’s and staff’s performance, while decreasing costs.
    • For example, a review study has shown that utilizing digital twins to manage the smooth coordination of several processes enabled a hospital to reduce the time in treatment of stroke patients by. 3
  • Risk management: Digital twins provide a safe environment to test the changes in system performance (staff numbers, operation room vacancies, device maintenance, etc.) which enables implementing data-driven strategic decisions in a complex and sensitive environment. 

Digital twin of the human body

Digital twins are also applied for modeling organs and single cells or an individual’s genetic makeup, physiological characteristics, and lifestyle habits to create personalized medicine and treatment plans. These replicas of the human body’s internal systems improve medical care and patient treatment by:

  • Personalized diagnosis:
    • Digital twins allow collection and usage of vital data (e.g. blood pressure, oxygen levels, etc.) at the individual level which helps individuals to track persistent conditions and, consequently, their priorities and interactions with doctors by providing basic information. Thus, such personalized data serve as the basis of clinical trials and research data at labs. 
    • By focusing on each individual separately, doctors do not derive treatments from large samples. Rather, they rely on customized simulations to track the reactions of each patient to different treatments, which increases the accuracy of the overall treatment plan. Despite the interest and increasing amount of efforts for personalized medicine, there are no digital twins applications for actual patients. One of the centers specialized on personalized medicine is Linköping University in Sweden who mapped mice RNA into a digital twin to predict the effects of medication.
  • Treatment Planning: With advanced modeling of the human body, doctors discover the pathology before the disorders are evident, experiment with treatments, and improve preparation for surgeries. 
Two doctors are viewing a replica of the human body with 3-D virtual reality glasses as an example of digital twin in healthcare.
Figure 1: Digital twin of human body

Digital twins for medicine and device development

Digital twin in healthcare can improve the design, development, testing, and monitoring of new drugs and medical devices. For example:

  • Drugs: Digital twins of drugs and chemical substances enable scientists to modify or redesign drugs considering particle size and composition characteristics to improve delivery efficiency. 
  • Devices: A digital twins of a medical device enables developers to test the characteristics or uses of a device, make alterations in design or materials, and test the success or failure of the modifications in a virtual environment before manufacturing. This significantly reduces the costs of failures, and enhances the performance and safety of the final product.
Two researchers are testing a new medication through digital twins, another use case for digital twin in healthcare.
Figure 2: Digital twin for medication

Manufacturing

Digital twins are most widely used in the manufacturing industry. Manufacturing relies on high-cost equipment that generates a high volume of data which facilitates creating digital twins. This is why digital twins technology has become one of the essential production planning tools. Digital twin applications in manufacturing are as follows:

Product development

Digital twins can help engineers test the feasibility of upcoming products before launching. According to the test results, engineers start producing or shift their focus to creating a feasible product.

Design customization

With digital twins, businesses can design various permutations of the product so that they can offer personalized products and services to their customers.

Shop floor performance improvement

A digital twin can be used to monitor and analyze end-products and help engineers see which products are defected or has lower performance than intended.

Predictive maintenance

Manufacturers leverage digital twins to predict potential downtimes of machines so that businesses minimize non-value adding maintenance activities and improve the overall efficiency of machines since technicians take action before a failure happens.

However, using digital twins for predictive maintenance tasks is not scalable as it is a machine-specific virtual replica and requires expensive data science talent to build and maintain twins.

For more info on digital twin applications in manufacturing, feel free to check our article about manufacturing AI where we explain each AI application.

In aerospace and automotive manufacturing, there are further applications of digital twins:

Aerospace

Before digital twins, physical twins were used in aerospace engineering. An example is Apollo 13 program in the 1970s where NASA scientists on earth were able to simulate the condition of the ship and find answers when critical issues arose. Later in 2002, the digital twin concept is introduced by John Vickers from NASA.

Today the importance of digital twins in the aerospace industry is acknowledged by experts that 75% of air force executives have cast the vote of confidence in favor of the digital twin, according to Business Wire’s survey report.4 Some applications of digital twins in the automotive industry are road testing and vehicle maintenance.

For more on digital twin applications in manufacturing, feel free to watch the video of Dr. Norbert Gaus who is head of R&D in Automation and Digitalization at Siemens. He is explaining how digital twins help streamline the production process in the real world and providing examples:

Retail

Customer modeling & simulations

Retailers can create digital twins of customer personas to improve the customer experience they deliver. For example, retailers can provide ideal fashion clothing products to customers based on their digital twin models.

Today, businesses use digital twins in numerous ways from product development to operational performance improvement. The digital twin market is expected to grow to $73.5 billion by 2027, at a CAGR of 60.6%. Increased digitization and IoT adoption are making it easier for businesses to build accurate digital twins and drive adoption of the technology.

What is a digital twin?

A digital twin is a virtual/ digital replica of physical objects such as devices, people, processes, or systems that help businesses make model-driven decisions. The purpose of a digital twin is to run cost-effective simulations.

The digital twin technology uses IoT sensors, log files and other relevant information to collect real world data for accurate modeling of real-world assets. These models are then combined with AI-powered analytics tools in a virtual setting.

3 Types of digital twins

There are three main types of digital twins:

  • Product Twins: Digital twin prototype of a physical object enables run-in scenarios to predict potential issues and optimize product quality. 
  • Process Twins: Process digital twins, also known as a digital twin of an organization (DTO), can help design, plan and improve processes to obtain best outcome.
  • System Twins: Virtual replicas of systems obtain information generated by systems to manage and optimize them. 

Why are digital twins important now?

Digital twins can improve enterprises’ data-driven decision-making processes since they rely on real-time and historical data to simulate, diagnose and predict. Businesses use the digital twin technology to understand the state of the physical asset, respond to changes, improve operations, and add value to the systems.

According to a survey, organizations implementing IoT already use digital twins (13%)  or plan to use it within a year (62%).5 Digital twins are helpful for growing smart city, urban space and autonomous things (AUT).

In a review study, researchers collected academic publications that contain digital twin as a keyword for 5 years period.Among these academic articles, top digital twin use cases were found for urban spaces and smart cities. 

The number of articles that contain digital twins are categorized according to the digital twin application areas. The urban spaces and smart cities hold the largest share with 47%, followed by manufacture with 17%, reviews with 14%, engineering by 12%, automotive with 8% and aerospace and medicine with 1%.
Figure 3: The publications on digital twin by use case/ application

How does a digital twin work?

These digital assets can be created even before an asset is built physically. Regardless of when it is created, the process of creating a virtual twin has basic steps:

  1. Research the physical object or system that will be mimicked
  2. Integrate sensors into physical assets or monitor log files and other sources to collect sensor data
  3. All this collected information along is integrated into the virtual model with AI algorithms
  4. By applying analytics into these models, data scientists and engineers get relevant insights regarding the physical asset.

These basic steps required to create digital twin simulations include major technologies which are the components of fourth industrial revolution (See Figure 1). 

Sensors, IoT, Cloud Computing, AI & simulations are five innovative technologies that are essential to generate digital twins
Figure 4: Digital twin enabling technologies, Source: MDPI

What are the benefits of digital twins?

Digital twins are commonly used in manufacturing and provide these benefits:

  • Lower maintenance costs via predictive maintenanceDigital twins enable businesses to understand potential sources of failure so that businesses minimize non-value adding maintenance activities
  • Improved productivity: Gartner predicts that industrial companies could see a 10 percent improvement in effectiveness via digital twins. This is due to reduced downtime due to predictive maintenance and improved performance via optimization.
  • Faster production times: IDC claims that businesses who invest in digital twin technology will see a 30 percent improvement in cycle times of critical processes including production lines.

An emerging area for digital twins is creating digital twins of entire businesses by leveraging operational data, referred as a digital twin of an organization (DTO). Benefits in this area include:

  • Improved business outcomes: Digital twins enable businesses to be more resilient to shocks thanks to virtual representations and this can translate into more enduring customer relationships and profitability.
  • Improved customer satisfaction: A digital twin allows users to gain a deeper understanding about their services, potential disruptions and customers’ needs. As a result, businesses can deliver better, more consistent services that eventually enhance the customer experience.

What is the relation between AI and digital twins?

Artificial intelligence and digital twins have a mutualist relation where both contribute to each other.

Digital twins can help businesses generate simulated data that can be used to train AI models. Artificial intelligence can also benefit from digital twins since digital twins can virtually create an environment for machine learning test scenarios. Depending on the utility score of virtual environment data scientists and engineers can deploy artificial intelligence solutions.

Digital twins can benefit from artificial intelligence. AI and machine learning algorithms enable businesses both to build some digital twins and also to process a large amount of data collected from digital twins. For example, by leveraging AI capabilities with digital twins, engineers can accelerate the design processes by quickly evaluating many possible design alternatives.

What are the leading digital twin tools?

This is a list of digital twin providers, excluding digital twin of an organization vendors.

  • Akselos
  • Ansys Twin Builder
  • Autodesk Digital Twin
  • Bosch IoT Suite
  • CONTACT Elements for IoT
  • Flutura Decision Science
  • IoTIFY
  • Oracle IoT Production Monitoring Cloud
  • Predix
  • ScaleOut Digital Twin Builder
  • Seebo
  • ThingWorx Operator Advisor.

Conclusion

Digital twins have been helpful to mirror, monitor, and optimize real-world systems virtually. From smart factories and cities to healthcare and energy, these use cases show how digital twins can drive data-driven decisions and improve performance.

Their success, however, relies on accurate models, real-time data integration, and the right mix of AI technologies. As digital twin adoption grows, their value will hinge on clear objectives, robust design, and integration into broader digital strategies.

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Cem has been the principal analyst at AIMultiple since 2017. AIMultiple informs hundreds of thousands of businesses (as per similarWeb) including 55% of Fortune 500 every month.

Cem's work has been cited by leading global publications including Business Insider, Forbes, Washington Post, global firms like Deloitte, HPE and NGOs like World Economic Forum and supranational organizations like European Commission. You can see more reputable companies and resources that referenced AIMultiple.

Throughout his career, Cem served as a tech consultant, tech buyer and tech entrepreneur. He advised enterprises on their technology decisions at McKinsey & Company and Altman Solon for more than a decade. He also published a McKinsey report on digitalization.

He led technology strategy and procurement of a telco while reporting to the CEO. He has also led commercial growth of deep tech company Hypatos that reached a 7 digit annual recurring revenue and a 9 digit valuation from 0 within 2 years. Cem's work in Hypatos was covered by leading technology publications like TechCrunch and Business Insider.

Cem regularly speaks at international technology conferences. He graduated from Bogazici University as a computer engineer and holds an MBA from Columbia Business School.

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