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Top 6 AS2 Software

Cem Dilmegani
Cem Dilmegani
updated on Sep 29, 2025

Choosing the most cost-effective AS2 software can be challenging given the many options available. To assist, we’ve compiled a list of top managed file transfer tools that support AS2:

What are our criteria for choosing the top As2 Software? 

  • User Reviews: We preferred solutions that received feedback on B2B review platforms such as G2 and Capterra, indicating a significant market presence validated by real user experiences.
  • Employee Size: Given the connection between a company’s income and its number of employees, we focused on businesses with more than 50 employees, as reported on LinkedIn.

Jscape MFT

JSCAPE MFT Server supports AS2 file transfers, ensuring secure and standardized B2B data exchange. It is Drummond-certified for AS2, providing encryption, digital signatures, and MDNs for data integrity and non-repudiation. For OFTP2, it offers high-speed transmission, compression, and encryption, making it an ideal solution for the automotive and manufacturing industries.

JSCAPE MFT server offers:

  • Encryption for secure data transmission
  • Multiple authentication methods for enhanced security
  • Automation capabilities for streamlined workflows
  • Support for various file transfer protocols ensuring compatibility
  • Auditing and logging for compliance purposes
  • High availability options for uninterrupted service
  • Integration with other systems through APIs
  • Security enhancements such as IP whitelisting

Cleo Integration Cloud

Cleo Integration Cloud provides business file transfer services, particularly for logistics, manufacturing, and wholesale industries.

Cleo’s platform stands out for its ability to enhance business agility and improve partner relationships through end-to-end transaction visibility and proactive error resolution. Its user-friendly, low-code environment is designed for both IT and operations teams, offering pre-built integrations and an intuitive UI.

Globalscape EFT

Globalscape EFT is distinguished by its workflow automation for secure file transfers. Fortra’s Globalscape Enhanced File Transfer (EFT) enhances operational efficiency and compliance, ensuring the safe exchange of sensitive files.

GlobalSCAPE’s EFT platform utilizes AS2, among other protocols, to ensure secure data transfers, featuring non-repudiation and message integrity checks.

Globalscape EFT Overview

WinSCP

WinSCP is a file transfer solution tailored for Windows users. It supports protocols such as SFTP, FTP, WebDAV, and SCP. It excels in facilitating file transfers between local and remote systems, and its robust scripting capabilities and essential file management functions complement it.

WinSCP offers an intuitive interface that simplifies the complexity of file transfers, making it accessible for both technical and non-technical users.

Whether for routine file management tasks or advanced automated operations, WinSCP offers a suite of features that enhance productivity and protect sensitive data, making it a suitable choice for Windows-based file transfer needs.

Axway B2Bi

Axway B2B Integration provides AS2 capabilities integrated with managed file transfer and EDI processing. The platform addresses enterprise B2B requirements across multiple protocols and integration patterns.

Key Features:

  • AS2, AS4, OFTP, and secure file transfer protocols
  • Cloud and on-premises deployment options
  • Automated trading partner onboarding workflows
  • Advanced routing and transformation capabilities
  • High-availability and disaster recovery configurations
  • Comprehensive monitoring and analytics
  • Integration with enterprise applications and APIs
  • Compliance reporting and audit trails
  • Global support and professional services

Axway B2Bi handles organizations requiring enterprise-grade AS2 capabilities with extensive trading partner networks. The platform provides protocol handling, data transformation, and business process automation.

GoAnywhere MFT

GoAnywhere MFT is a secure file transfer automation software alternative that supports SFTP protocols. It enables users to automate file transfers efficiently and schedule workflows using either its built-in scheduler or existing scheduler software. The browser-based administrator enables the easy execution of authorized projects with a single click, streamlining workflow and file automation.

What are the important features of AS2 Software Solutions?

  • Data Encryption: AS2 software uses standard encryption methods to ensure that data is securely transmitted over the Internet, protecting sensitive information from unauthorized access.
  • Digital Signatures: It employs digital signatures to authenticate the sender of the data, ensuring the integrity and non-repudiation of the transmitted data.
  • Secure and Reliable Transport: AS2 operates over HTTPS, adding an additional layer of security through SSL/TLS. This ensures that data in transit is encrypted and secure from endpoint to endpoint.
  • Interoperability: AS2 software allow for interoperability between different systems and software, facilitating seamless data exchange between businesses regardless of their underlying technologies.
  • Asynchronous and Synchronous Communication: AS2 supports both asynchronous communication, where the response (MDN) is not immediately required and can be sent later, and synchronous communication, where the MDN is sent immediately after the message is received and processed.
  • Payload Agnosticism: AS2 software are not limited to any specific data format, making it versatile for transmitting various types of documents, such as EDI, XML, JSON, binary files, etc.

Source: Advanced Systems Concepts1

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Principal Analyst
Cem Dilmegani
Cem Dilmegani
Principal Analyst
Cem has been the principal analyst at AIMultiple since 2017. AIMultiple informs hundreds of thousands of businesses (as per similarWeb) including 55% of Fortune 500 every month.

Cem's work has been cited by leading global publications including Business Insider, Forbes, Washington Post, global firms like Deloitte, HPE and NGOs like World Economic Forum and supranational organizations like European Commission. You can see more reputable companies and resources that referenced AIMultiple.

Throughout his career, Cem served as a tech consultant, tech buyer and tech entrepreneur. He advised enterprises on their technology decisions at McKinsey & Company and Altman Solon for more than a decade. He also published a McKinsey report on digitalization.

He led technology strategy and procurement of a telco while reporting to the CEO. He has also led commercial growth of deep tech company Hypatos that reached a 7 digit annual recurring revenue and a 9 digit valuation from 0 within 2 years. Cem's work in Hypatos was covered by leading technology publications like TechCrunch and Business Insider.

Cem regularly speaks at international technology conferences. He graduated from Bogazici University as a computer engineer and holds an MBA from Columbia Business School.
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Researched by
Sena Sezer
Sena Sezer
Industry Analyst
Sena is an industry analyst in AIMultiple. She completed her Bachelor's from Bogazici University.
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We follow ethical norms & our process for objectivity. AIMultiple's customers in Enterprise Software include Redwood Software, Stonebranch, Cerberus FTP Server, Files.com, GoAnywhere, JSCAPE.